Supplement for: Heterogeneous molecular processes among the causes of how sequence similarity scores can fail to recapitulate phylogeny
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Heterogeneous molecular processes among the causes of how sequence similarity scores can fail to recapitulate phylogeny
Sequence similarity tools like Basic Local Alignment Search Tool (BLAST) are essential components of many functional genetic, genomic, phylogenetic and bioinformatic studies. Many modern analysis pipelines use significant sequence similarity scores (p- or E-values) and the ranked order of BLAST matches to test a wide range of hypotheses concerning homology, orthology, the timing of de novo gene...
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